We propose Online-InReaCh, the first fully unsupervised online method for detecting and localizing anomalies on-the-fly in image sequences while following non-stationary distributions. Previous anomaly detection methods are limited to supervised one-class classification or are unsupervised but still pre-compute their nominal model. Online-InReaCh can operate online by dynamically maintaining a nominal model of commonly occurring patches that associate well across image realizations of the underlying nominal distribution while removing stale previously nominal patches. Online-InReaCh, while competitive in previous offline benchmarks, also achieves 0.936 and 0.961 image- and pixel-wise AUROC when tested online on MVTecAD, where 23.8% of all randomly sampled images contain anomalies. Online-InReaCh's performance did not correlate with anomaly proportion even to 33.5%. We also show that Online-InReaCh can integrate new nominal structures and distinguish anomalies after a single frame, even in the worst-case distribution shift from one training class to a new previously unseen testing class.